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A quantitative comparison of basal ganglia neuronal activities of normal and Parkinson's disease model rats

✍ Scribed by Sang Baek Ryu; Eun Kyung Bae; Yong Sup Hwang; Hyun Joo Lee; ChangKyun Im; Jin Woo Chang; Hyung-Cheul Shin; Kyung Hwan Kim


Book ID
118488069
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
684 KB
Volume
505
Category
Article
ISSN
0304-3940

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## Abstract ## Background Dopamine depletion of the striatum is one of the hallmarks of Parkinson's disease. The loss of dopamine upregulates GAD67 expression in the striatal projection neurons and causes other changes in the activity of the basal ganglia circuit. ## Methods To normalize the GAD