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A quantitative assay for JAK2V617F mutation in myeloproliferative disorders by ARMS-PCR and capillary electrophoresis

✍ Scribed by Vannucchi, A M; Pancrazzi, A; Bogani, C; Antonioli, E; Guglielmelli, P

Book ID: 110056728
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 219 KB
Volume: 20
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2404209

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## Abstract Diagnosis of the myeloproliferative disorders, polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF) is difficult due to lack of diagnostic markers. Recently, the acquisition of a mutation in the Janus kinase 2 (__JAK2__) gene by hemopoietic cells has