A probabilistic approach to the kinetics of the polymerase chain reaction (PCR) is developed. The approach treats the primer extension step of PCR as a microscopic Markov process in which the molecules of deoxy-nucleoside triphosphate (dNTP) are bound to the 3 end of the primer strand one at a time.
A quantitative approach for polymerase chain reactions based on a hidden Markov model
β Scribed by Nadia Lalam
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 272 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0303-6812
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