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A Quantitative Analysis and Chemical Approach for the Reduction of Nonspecific Binding Proteins on Affinity Resins

✍ Scribed by Tamura, Tsuruki; Terada, Tomohiro; Tanaka, Akito


Book ID
120994636
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
202 KB
Volume
14
Category
Article
ISSN
1043-1802

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## Abstract One of the biggest challenges in the β€œ__in silico__” screening of enzyme ligands is to have a protocol that could predict the ligand binding free energies. In our group we have developed a very simple screening function (referred to as solvent accessibility free energy of binding predic