A Putatively Unfeasible Heck Reaction − From Cyclopentenones to Annulated Ring Systems

✍ Scribed by Gerald Dyker; Hardy Markwitz; Gerald Henkel

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 359 KB
• Volume: 2001
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/1099-0690(200107)2001:13<2415::aid-ejoc2415>3.0.co;2-4

✦ Synopsis

Annulation / Palladium / Allylic compounds / Alcohols / Michael addition 2-Iodocyclopentenones undergo a Heck reaction with allylic and homoallylic alcohols, in acceptable yields, to give dicarbonyl compounds useful for the construction of annulated cyclopentanones. In contrast, the corresponding iodo-substi-