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A putative role for the plasma membrane potential in the control of the expression of the gene encoding the tomato high-affinity potassium transporter HAK5

✍ Scribed by Manuel Nieves-Cordones; Anthony J. Miller; Fernando Alemán; Vicente Martínez; Francisco Rubio


Publisher
Springer
Year
2008
Tongue
English
Weight
395 KB
Volume
68
Category
Article
ISSN
0167-4412

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## Abstract Mutations in the gene encoding ClC‐5 lead to X‐linked hypercalciuric nephrolithiasis (XLHN), characterized by proteinuria, hypercalciuria, and phosphaturia. In renal proximal tubule cells, ClC‐5 was identified as an important player in endocytosis, which ensures reabsorption of filtered