N-glycosylation of the Xenopus laevis Cl
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Sandra Schmieder; Stéphanie Bogliolo; Jordi Ehrenfeld
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Article
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2006
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John Wiley and Sons
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English
⚖ 295 KB
👁 2 views
## Abstract Mutations in the gene encoding ClC‐5 lead to X‐linked hypercalciuric nephrolithiasis (XLHN), characterized by proteinuria, hypercalciuria, and phosphaturia. In renal proximal tubule cells, ClC‐5 was identified as an important player in endocytosis, which ensures reabsorption of filtered