A pulsed N.M.R. study of D2O bound to 1,2 dipalmitoyl phosphatidylcholine

✍ Scribed by B.A. Cornell; J.M. Pope; G.J.F. Troup

• Book ID: 103040695
• Publisher: Elsevier Science
• Year: 1974
• Tongue: English
• Weight: 972 KB
• Volume: 13
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(74)90035-8

✦ Synopsis

Spin lattice relaxation times in both the lab and rotating frame, have been measured for deuterons (2 H) in a number of unsonicated dispersions of 1,2 dipalmitoyl phosphatidylcholine in D 20 over a range of resonant frequencies from 13 MHz to 1 MHz for temperatures from -20°C to 65°C.

The proton (1 H) spin lattice relaxation time for the lecithin was measured for resonant frequencies of 8.5 MHz, and 40 MHz over a similar range of temperatures.

The results agree with broadline measurements by Salsbury et al.

[ 1 ], and for the liquid crystal phase are consistent with an anisotropic tumbling model of the water molecules bound to the lecithin headgroup. This tumbling occurs with correlation times of <~ 10 -10 sec and ~ 10 -6. sec about axes parallel to and perpendicular to the bisector of the D-O-D angle within a D20 molecule, hydrogen bonded to the negatively charged phosphate headgrou p.