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A pulsatile drug delivery system based on rupturable coated hard gelatin capsules

โœ Scribed by T. Bussemer; A. Dashevsky; R. Bodmeier

Book ID
113690396
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
719 KB
Volume
93
Category
Article
ISSN
0168-3659

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pH-sensitive hydrogels based on methacrylic acid (MAA) and poly(ethylene glycol) macromonomer (PEGMEMA) entrapping diltiazem hydrochloride (DILรHCl) were synthesized inside soft gelatin capsules for use as a new dosage form for oral drug administration. Different monomer compositions were used to ev