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A prototype of a rationally designed chemically powered Brownian motor

โœ Scribed by J.P. Sestelo; T.R. Kelly


Book ID
106024492
Publisher
Springer
Year
2002
Tongue
English
Weight
181 KB
Volume
75
Category
Article
ISSN
1432-0630

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Rational design of a targeted combinator
โœ Weifan Zheng; Sung Jin Cho; Alexander Tropsha ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 241 KB ๐Ÿ‘ 2 views

We describe a new computational approach, called Focus-2D, to the rational design of targeted combinatorial chemical libraries. This approach is based on the hypothesis that structurally similar compounds display similar biological activity profiles. Building blocks that are used in a combinatorial