The aza-robinson annulation: An applicat
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Francis G. Fang; Maurizio Prato; Guncheol Kim; Samuel J. Danishefsky
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Article
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1989
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Elsevier Science
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French
⚖ 258 KB
Annulation of diazomethylvinylketone (4a) with a variety of secondary thiolactams provides a novel route to dihydro-y-pyridones. This approach has been applied to the synthesis of iso-A58365A ( ), the y-pyridone analog of the ACE inhibitor, A58365A (1). We have recently described a novel route to