Enzymatic synthesis of a sialyl Lewis X
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Chun-Hung Lin; Makoto Shimazaki; Chi-Huey Wong; Mamoru Koketsu; Lekh Raj Juneja;
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Article
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1995
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Elsevier Science
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English
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A dimeric sialyl Lewis X (SLex) glycopeptide was synthesized enzymatically in three steps from an N-linked oligosaccharide prepared from egg yolk. Treatment of delipidated hen egg yolk with the protease Orientase and neuraminidase gave a dimeric N-acetyllactosamine-containing oligosaccharide linked