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A protein activator of the plasma membrane Ca++-ATPase of heart sarcolemma

โœ Scribed by Leslie J. Reinlib; Arthur F. Clark; Ernesto Carafoli


Publisher
Springer US
Year
1984
Tongue
English
Weight
848 KB
Volume
16
Category
Article
ISSN
0145-479X

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The purified Ca2+/Mg2+ ATPase from rat heart plasma membrane was activated by Ca2+ and Mg2+ with Ka values of 1.47 mM and 2.51 mM, respectively; other divalent cations also activated the enzyme but to a lesser extent. Divalent cations like Cu2+, Zn2+, Ni2+, Cd2+ were potent inhibitors of the enzyme