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A protective effect of the synthetic coumarine derivative Cloricromene against DNB-colitis in the rat

✍ Scribed by Walter Fries; Emanuela Mazzon; Sergio Sturiale; Maria R Giofré; Maria A Lo Presti; Salvatore Cuzzocrea; Giuseppe M Campo; Achille P Caputi; Giuseppe Longo; Giacomo C Sturniolo

Book ID: 116717292
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 140 KB
Volume: 74
Category: Article
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2003.10.016

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## Abstract The immunosuppressive agent cyclosporine A (CsA) has been reported to exert measurable hepatotoxic effects. One of the causes leading to hepatotoxicity is thought to be reactive oxygen radical formation. The aim of this study was to investigate the effects of __N__‐acetylcysteine (NAC)