Seventy-six patients with advanced breast cancer were entered into the current study. They were randomized to receive either idarubicin (IDA) 45 mg/m2 orally or doxorubicin (DX) 75 mg/m2 intravenously (IV), both drugs being administered every 3 weeks. Among 37 evaluable patients who received DX trea
A prospective trial of the tnm classification of breast cancer by the regional cancer treatment centres in Ontario, 1960–1964
✍ Scribed by E. N. Mackay; A. H. Sellers
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- French
- Weight
- 598 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
As its contribution to the 1960–64 clinical trial of the TNM Classification of breast cancer, The Ontario Cancer Treatment and Research Foundation reviewed in detail the distribution and 5‐year survival of 1,846 female patients classified according to TNM criteria. While further consideration of some aspects is required (for example, differentiation between skin infiltration and skin ulceration in T3, and the possible reallocation of certain T4 and N3 categories in stage IV), the UICC criteria in general appeared reasonably homogeneous within T and N categories, and sufficiently distinctive between categories. Summary tables showing statistically significant findings are given; basic tables for comparison or pooling with other series are available on request. The Ontario experience is strongly in favour of the general principles of the classification.
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