A prospective randomised controlled study of patient-controlled propofol sedation in phobic dental patients

✍ Scribed by N. M. Girdler; D. Rynn; J. P. Lyne; K. E. Wilson

• Book ID: 104456285
• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 184 KB
• Volume: 55
• Category: Article
• ISSN: 0003-2409
• DOI: 10.1046/j.1365-2044.2000.01279.x

✦ Synopsis

The safety and effectiveness of patient‐controlled propofol sedation was prospectively assessed in 18 healthy, phobic dental patients. Using a randomised, crossover design each patient received two sessions of equivalent dental treatment under patient‐controlled or clinician‐controlled propofol sedation. The patient‐controlled technique used 29.8% less drug (time‐weighted dose) than the clinician‐controlled method (p = 0.011). There was a high correlation between number of demands and number of doses actually infused during the patient‐controlled technique (r = 0.99, p < 0.001). Clinically, the level of sedation was lighter and the degree of operator satisfaction was higher with patient‐controlled sedation. Blood pressure and arterial oxygen saturation showed minimal changes and remained within normal ranges during both techniques. Patient‐controlled sedation produced a greater reduction in dental and general anxiety compared with clinician‐controlled sedation, but the difference did not reach statistical significance. Three times the number of patients expressed a preference for the patient‐controlled, compared with the clinician‐controlled, technique. Patient‐controlled sedation provides safe and acceptable intra‐operative anxiolysis for phobic dental patients, but with reduced propofol dosage.