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A proposed staging system for chronic myeloid leukemia

✍ Scribed by Dennis W. Ross; Richard D. Brunning; Hagop M. Kantarjian; H. Phillip Koeffler; Howard Ozer

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
335 KB
Volume
71
Category
Article
ISSN
0008-543X

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## Abstract Chronic myeloid leukemia (CML) occurs from childhood to old age. The adult form is characterized by the presence of Philadelphia chromosome resulting from bcr/abl translocation. The BCR–ABL fusion proteins are immunogenic, and the junctional sequences show unique HLA class I and class I