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A proposed mechanism of benzene toxicity: Formation of reactive intermediates from polyphenol metabolites

โœ Scribed by William F. Greenlee; James D. Sun; James S. Bus

Book ID
113205605
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
716 KB
Volume
59
Category
Article
ISSN
0041-008X

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The excretion and biotransformation of [14C] 1,1-dichloroethylene (vinylidene chloride, VDC) after administration of a single oral dose has been investigated in female rats. Seventy-two hours after a dose of 0.5, 5.0, and 50.0 mg/kg, 1.26, 9.70, 16.47%, respectively, are exhaled as unchanged VDC, an