𝔖 Bobbio Scriptorium
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A proposed interaction model of the insulin molecule with its receptor

✍ Scribed by Dong-cai Liang; Wen-rui Chang; Zhu-li Wan


Book ID
107944248
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
646 KB
Volume
50
Category
Article
ISSN
0301-4622

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Insulin causes rapid phosphorylation of the fl subunit (M, = 95,000) of its receptor in broken cell preparations. This occurs on tyrosine residues and is due to activation of a protein kinase which is contained in the receptor itself. In the intact cell, insulin also stimulates the phosphorylation o