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A proposal for the biosynthesis of the clavulones, a new family of eicosanoids

✍ Scribed by E. J. Corey

Publisher
Springer
Year
1983
Tongue
English
Weight
194 KB
Volume
39
Category
Article
ISSN
1420-682X

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Identification of a new eicosanoid from
Identification of a new eicosanoid from in vitro biosynthetic experiments with clavularia viridis. Implications for the biosynthesis of clavulones.
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A cell-free homogenate of Clavularia viridis converts tritiated arachidonic acid into a new eicosanoid identified as 5 (free acid) by chemical and chromatographic studies in comparison with synthetic substances. The isolation of 4, suggests a novel, non-prostanoid type pathway for the biosynthesis o