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A program for multiple hypothesis tests

✍ Scribed by Mikel Aickin

Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
348 KB
Volume
15
Category
Article
ISSN
0010-4809

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✦ Synopsis

This is a description of the program DIGRAPH which assists in computing a new p value that may be used when many hypotheses are to be tested simultaneously. Substantially more significance statements can be made using this procedure than by using another omnibus method, the Bonferroni procedure.

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## Abstract In case‐control studies of unrelated subjects, gene‐based hypothesis tests consider whether any tested feature in a candidate geneβ€”single nucleotide polymorphisms (SNPs), haplotypes, or bothβ€”are associated with disease. Standard statistical tests are available that control the false‐pos