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A program for maximum likelihood estimation and likelihood ratio tests in one-locus ABO-like systems based upon population phenotype data

✍ Scribed by S.Olesen Larsen


Publisher
Elsevier Science
Year
1979
Weight
253 KB
Volume
9
Category
Article
ISSN
0010-468X

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✦ Synopsis


Phenotypes in an ABO-like system of a number of genetically-independent persons from a number of populations are supposed to be observed. The program which is written in FORTRAN calculates maximum likelihood estimates of gene frequencies and their standard errors in each population and in the populations taken together. Furthermore the program calculates expected values and likelihood ratio and goodness of fit chi-square tests of Hardy-Weinberg equilibrium. If several subpopulations are pooled together a likelihood ratio test of homogeneity is performed.

Gene-frequencies

Maximum likelihood ABO-like systems Likelihood ratio test Computer program