A new computer program called BuildQSAR has been designed to help the QSAR practitioner on the task of building and analyzing quantitative models through regression analysis. The main part of the program is a spreadsheet, in which the user can enter with the data set composed by the structure deยฎnit
A probit analysis program for the personal computer
โ Scribed by Gary M. Schoofs; Calvin C. Willhite
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 335 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0260-437X
No coin nor oath required. For personal study only.
โฆ Synopsis
Application software for economical and convenient calculation of median effective doses, confidence limits, potency ratios and slopes of quantal dose-response curves using a microcomputer is presented. The PASCAL language program is stored on diskette and it is compatible with many commercially available microcomputer systems. The program will simultaneously calculate the parameters for up to 20 different treatments and a total of 100 doses. Comparisons between the results of calculations of the LD50 of thiopental in mice using the PASCAL program, a modem-accessed commercially available probit analysis program and three, widely accepted manual calculation methods are made. The results of calculations of parallelism and the potency ratio between thiopental and phenobarbital-induced death in mice are shown.
๐ SIMILAR VOLUMES
## Abstract A new computer program has been designed to build and analyze quantitativeโstructure activity relationship (QSAR) models through regression analysis. The user is provided with a range of regression and validation techniques. The emphasis of the program lies mainly in the validation of Q