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A probable conformational difference between recombinant and urinary erythropoietins

โœ Scribed by Charles K.-H. Kung; Eugene Goldwasser


Book ID
101228754
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
67 KB
Volume
28
Category
Article
ISSN
0887-3585

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โœฆ Synopsis


Urinary and recombinant human erythropoietin differ with respect to ease of iodination, inactivation by iodination, second derivative and circular dichroic spectra, rate of inactivation by trypsin and glycosylation pattern. All of these differences are compatible with a significant difference in conformation of these two forms of erythropoietin.

Proteins 28:94-98, 1997 r 1997 Wiley-Liss, Inc.


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