✦ LIBER ✦

A probabilistic method for identifying rare variants underlying complex traits

✍ Scribed by Jiayin Wang, Zhongmeng Zhao, Zhi Cao, Aiyuan Yang, Jin Zhang

Book ID: 120676815
Publisher: BioMed Central
Year: 2013
Tongue: English
Weight: 246 KB
Volume: 14
Category: Article
ISSN: 1471-2164
DOI: 10.1186/1471-2164-14-S1-S11

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Rare Variant Association Analysis Method

Rare Variant Association Analysis Methods for Complex Traits

✍ Asimit, Jennifer; Zeggini, Eleftheria 📂 Article 📅 2010 🏛 Annual Reviews 🌐 English ⚖ 235 KB

A data-driven method for identifying rar

A data-driven method for identifying rare variants with heterogeneous trait effects

✍ Qunyuan Zhang; Marguerite R. Irvin; Donna K. Arnett; Michael A. Province; Ingrid 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB

Collapsing multiple variants into one variable and testing their collective effect is a useful strategy for rare variant association analysis. Direct collapsing, however, is not valid or may significantly lose power when a group of variants to be collapsed have heterogeneous effects on target traits