A Priori Theoretical Prediction of Selectivity in Asymmetric Catalysis: Design of Chiral Catalysts by Using Quantum Molecular Interaction Fields

A Priori Theoretical Prediction of Selec

✍ James C. Ianni; Venkatachalam Annamalai; Puay-Wah Phuan; Manoranjan Panda; Maris 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB

Much effort has been devoted toward the development of asymmetric catalysts for the synthesis of chiral compounds in pure form. [1] Despite this body of work, the science of asymmetric catalysis remains far from exact, and the process of finding a new catalyst usually requires a large investment of