## Background: Early-onset familial alzheimer's disease (eofad) is linked to mutations in three autosomal dominant genes: ps1, ps2 and app. the clinical presentation and age of onset of mutations is variable. ## Objectives: The aim of this report is to describe a novel ps1 mutation believed to be
β¦ LIBER β¦
A presenilin-1 mutation (T245P) in transmembrane domain 6 causes early onset Alzheimer's disease
β Scribed by Terri Edwards-Lee; Johnny Wen; Jason Bell; John Hardy; Julia Chung; Parastoo Momeni
- Book ID
- 116768456
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 158 KB
- Volume
- 398
- Category
- Article
- ISSN
- 0304-3940
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