✦ LIBER ✦

A preliminary study of baclofen-induced growth hormone release in generalised social phobia

✍ Scribed by Rita M. Condren; Jim V. Lucey; Jogin H. Thakore

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 70 KB
Volume: 18
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.443

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Objective

The authors sought to examine central GABA~B~ receptor responses in patients with generalised social phobia using the growth hormone (GH) response to baclofen.

Method

Baclofen 20 mg was administered to 15 patients and 15 healthy matched controls and plasma growth hormone was monitored over a 3 h period.

Results

The GH response in patients was significantly reduced in comparison to that of controls when calculated as both area under the curve (AUC) and delta (Δ) response.

Conclusions

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