Rigid inhibitors suffer a smaller loss of conformational entropy when they bind to a macromolecular receptor than fheir acyclic counterparts. They can also be useful for elucidating pharmacophores due to their reduced conformational space and may be more amenable to synthesis. Computational approach
A pragmatic approach to computer-assisted system building
โ Scribed by Oscar Barros
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 899 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0164-1212
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
This article presents a microcomputer-based, interactive, menu-driven visual software package developed to investigate design, off-design, and transient operations of single-and twin-shaft industrial gas turbines, providing mechanical engineering students with the opportunity for flexible operation
Computer programs have been designed to generate three dimensional models of protein structures. Depth perception is achived by decreasing the line intensity of the covalent bonds as the atoms move further from the observer. The molecular models could be constructed from x-ray data or from simulated