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A practical synthesis from siastatin B of (3S,4S,5R,6R)-4,5-dihydroxy-6-(trifluoroacetamido)piperidine-3-carboxylic acid having antimetastatic activity in mice

✍ Scribed by Takahiko Satoh; Yoshio Nishimura; Shinichi Kondo; Tomio Takeuchi


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
353 KB
Volume
286
Category
Article
ISSN
0008-6215

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✦ Synopsis


In the course of our studies [1] investigating the relationship between the structure and biological activity of glycosidase inhibitors, we previously synthesized (3S,4S,5 R,6 R)-4,5-dihydroxy-6-(trifluoroacetamido)piperidine-3-carboxylic acid (1) [2]

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