Chiral cyclic β-amino esters. Part II: S
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J. Blot; A. Bardou; C. Bellec; M.-C. Fargeau-Bellassoued; J.P. Célérier; G. Lhom
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Article
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1997
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Elsevier Science
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French
⚖ 182 KB
Catalytic and chemical reductions of chiral pyrrolidine 13-enamino esters provides corresponding [3-amino esters with good to moderate diastereomer excesses. The unexpected major diastereomer 5 comes from a reduction process which amounts to an anti hydrogen addition.