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A Practical Method for the Synthesis of Highly Enantioenriched trans -1,2-Amino Alcohols

โœ Scribed by Birrell, James A.; Jacobsen, Eric N.

Book ID
120402545
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
322 KB
Volume
15
Category
Article
ISSN
1523-7060

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An efficient protocol for the synthesis of chiral polyhydroxy diacetylenic alcohols from chiral 4,5-O-isopropylidene propargyl chlorides using strong bases is described and is useful for the synthesis of biologically active natural products.