## Abstract Global effects in functional MRI are temporal modulations in signal intensity resulting from various scanner and subject phenomena. These effects contribute to the overall variance, reducing the effect size associated with an experimental paradigm. Statistical estimations that include a
A practical method for 2D multiple-animal MRI
✍ Scribed by Marc S. Ramirez; James A. Bankson
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 307 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Purpose
To investigate practical methods for achieving routine simultaneous 2D MRI of multiple animals in large‐bore experimental scanners.
Materials and Methods
Three four‐element array geometries were compared against a standard single‐coil configuration in terms of image quality, ease of use, and data efficiency using a four‐channel, 4.7 T small animal imaging system.
Results
A linear arrangement of volume resonators permits unobstructed animal preparation and use of an imaging protocol that is almost identical to the single‐coil configuration without requiring any image correction or other additional postprocessing. Resulting in vivo images were visually indistinguishable from those acquired through the single‐coil configuration.
Conclusion
The efficiency of animal studies employing 2D MRI techniques can be substantially improved by using a linear array of commercially available resonators. J. Magn. Reson. Imaging 2007;26:1162–1166. © 2007 Wiley‐Liss, Inc.
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