A Practical Enantioselective Total Synthesis of the Bengamides B, E, and Z.
โ Scribed by Robert K. Boeckman Jr.; Tammy J. Clark; Brian C. Shook
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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Enantioselective Total Synthesis of Reveromycin B. -The crucial steps to synthesize the title compound (VIII) include a modified Negishi coupling of alkyne (I) with iodide (II) and the Kishi-Nozaki coupling of aldehyde (IV) with iodide (V). The former coupling is more efficient and superior as compa