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A Practical and Green Approach towards Synthesis of Dihydropyrimidinones without Any Solvent or Catalyst

โœ Scribed by Ranu, Brindaban C.; Hajra, Alakananda; Dey, Suvendu S.


Book ID
118127102
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
56 KB
Volume
6
Category
Article
ISSN
1083-6160

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Parallel synthesis of dihydropyrimidinon
โœ Alessandro Dondoni; Alessandro Massi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 77 KB

An efficient synthesis of an array of 3,4-dihydropyrimidin-2-(1H)-ones using solid-supported ytterbium(III) reagent from aldehydes, 1,3-dicarbonyl compounds and urea (Biginelli reaction) under solvent-free conditions is described. Purification of each member of the library was carried out using a co