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A Possible Unitary Genetic Hypothesis for Alzheimer's Disease and Down Syndrome

โœ Scribed by MIRIAM SCHWEBER


Book ID
118722519
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
969 KB
Volume
450
Category
Article
ISSN
0890-6564

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Linkage studies in families with presenile onset of Alzheimer's disease (AD) indicated the presence of a predisposing gene on the proximal long arm of chromosome 21. We mapped four new loci in the candidate AD region using somatic cell hybrids. For three of the four loci, several restriction fragmen