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A possible difference in the mechanism of replication of moderately repeated nucleotide sequences in Chinese hamster ovary cells

โœ Scribed by Michael R. Mattern; Robert B. Painter

Book ID
118877294
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
616 KB
Volume
111
Category
Article
ISSN
0014-4827

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## Abstract An amino acid sequence variant is defined as an unintended amino acid sequence change and contributes to product heterogeneity. Recombinant monoclonal antibodies (MAbs) are primarily expressed from Chinese Hamster Ovary (CHO) cells using stably transfected production cell lines. Selecti