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A population study of Lesch–Nyhan disease in the UK

✍ Scribed by GILLIAN T MCCARTHY; ELIZABETH M GREEN; OLUWAFEMI OGUNBONA; H ANNE SIMMONDS; LYNETTE FAIRBANKS; TERRY POUNTNEY; ELIZABETH BRYANT


Book ID
111131582
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
142 KB
Volume
53
Category
Article
ISSN
0012-1622

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Lesch-Nyhan mutation: The influence of p
✍ Stephen Wood; Leonard Pinsky 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 603 KB

## Abstract In extracts of normal and Lesch‐Nyhan (LN) heterozygous skin fibroblast monolayer cultures, hypoxanthine‐guanine (H‐G) and adenine (A) phosphoribosyltransferase (PRT) activities are correlated. These activities vary concomitantly during the life cycle of a culture: Peak activities occur