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A Population-Genetic Test of Founder Effects and Implications for Ashkenazi Jewish Diseases

โœ Scribed by Montgomery Slatkin


Book ID
117854484
Publisher
American Society of Human Genetics
Year
2004
Tongue
English
Weight
860 KB
Volume
75
Category
Article
ISSN
0002-9297

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The success of prenatal carrier screening as a disease prevention strategy in the Ashkenazi Jewish (AJ) population has driven the expansion of screening panels as disease-causing founder mutations have been identified. However, the carrier frequencies of many of these mutations have not been reporte