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A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm

✍ Scribed by Golledge, Jonathan; Biros, Erik; Warrington, Nicole; Jones, Gregory T; Cooper, Matthew; van Rij, Andre M; Palmer, Lyle J; Norman, Paul E


Book ID
109849287
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
231 KB
Volume
19
Category
Article
ISSN
1018-4813

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## Abstract Because androgens likely play a key role in prostate growth and prostate cancer development, variants of genes involved in androgen biosynthesis may be related to prostate cancer risk. The enzyme P450c17Ξ±, encoded by the __CYP17__ gene, catalyzes the conversion of progesterone and pregn