A point mutation in the Nul gene of bacteriophage λ facilitates phage growth in Escherichia coli with himA and gyrB mutations

The gyrB gene product functions in both

The gyrB gene product functions in both initiation and chain polymerization of Escherichia coli chromosome replication: Suppression of the initiation deficiency in gyrB-ts mutants by a class of rpoB mutations

✍ Filutowicz, Marcin ;Jonczyk, Piotr 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 656 KB

A class of rpoB mutations is described which suppresses replication and transcription deficiency in gyrB-ts mutants shifted to a nonpermissive temperature. The compensatory effect of an altered subunit B of RNA polymerase (rpoB) for the gyrB defect, indicates that transcription is a primary target o