✦ LIBER ✦
A PLS QSAR analysis using 3D generated aromatic descriptors of principal property type: Application to some dopamine D2 benzamide antagonists
✍ Scribed by Ulf Norinder
- Publisher
- Springer Netherlands
- Year
- 1993
- Tongue
- English
- Weight
- 616 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0920-654X
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✦ Synopsis
A simple and computationally nonintensive technique based on principal component analysis of 3D fields to derive theoretical descriptors is presented. The descriptors are then applied to a quantitative structureactivity relationship study on some dopamine D2 antagonists of benzamide type.