A pilot study on hypoxia of squamous cell carcinoma in oral cavity
β Scribed by W. Liu; J. Shang; Y. Gao; C. Guo
- Book ID
- 116561184
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 93 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0901-5027
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## Abstract ## Objectives/Hypothesis: Previous studies have demonstrated a relationship between elevated serum squamous cell carcinoma (SCC) antigen (SCCβAg) levels and shorter survival in cancer patients. Few studies, however, have investigated the role of serum SCCβAg levels in oral SCC (OSCC).
The ABH isoantigen was investigated in 80 patients with squamous cell carcinoma of the oral cavity and in their 46 affected lymph nodes. Isoantigen deletion shows a characteristic pattern of benign to malignant transformation of oral cancer. Total loss of isoantigen was found in anaplastic tumours,