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A Pilot Study of Oxcarbazepine Versus Acamprosate in Alcohol-Dependent Patients

✍ Scribed by Bernhard Croissant; Alexander Diehl; Oliver Klein; Sergio Zambrano; Helmut Nakovics; Andreas Heinz; Karl Mann

Book ID
109123482
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
120 KB
Volume
30
Category
Article
ISSN
0145-6008

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## Abstract ## Introduction Oxcarbazepine (OXC) reduces high‐voltage‐activated calcium currents, thus reducing glutamatergic transmission at corticostriatal synapses. This effect on NMDA glutamatergic transmission may play a role against the increased glutamatergic transmission determined by alcoh