The quantitation of hepatitis C virus (HCV) viremia RNA is measured by molecular techniques such as comcan be helpful in the diagnosis, therapy, and monitoring petitive reverse-transcription polymerase chain reacof patients with chronic hepatitis C. A sensitive and tion and branched DNA (bDNA) signa
A pilot study of corticosteroid priming for lymphoblastoid interferon alfa in patients with chronic hepatitis C
β Scribed by K Chayama; A Tsubota; M Kobayashi; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Y Arase; S Saitoh; N Murashima; K Ikeda; H Kumada
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 183 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
β¦ Synopsis
These factors are important, because they may influpolymerase chain reaction.
ence the outcome of treatment. Furthermore, the study From the Department of Gastroenterology, Toranomon Hospital, Okinaka did not evaluate the effect of treatment on HCV clear-Memorial Institute for Medical Research, Toranomon, Minato-ku, Tokyo, Japan.
ance. We conducted a randomized open clinical trial
π SIMILAR VOLUMES
Twelve children with chronic non-A, non-B hepatitis were entered in a pilot trial of recombinant interferon-alpha. Although all the children had hepatitis C virus RNA in serum, only five had antibodies against this virus. Children received 3 MU/m2 body surface area interferon-alpha 3 times/wk for 6
## Steroid priming does not potentiate the effect of IFN-a. The comparative efficacy of prednisolone followed by (HEPATOLOGY 1996;23:700-707.) interferon alfa (IFN-a) versus IFN-a alone in enhancing the rate of antibody to hepatitis B e antigen (anti-HBe) seroconversion has not been evaluated in a
JANICE ALBRECHT, 12 AND THE HEPATITIS INTERVENTIONAL THERAPY GROUP\* with continued therapy at that dose; however, a propor-To evaluate response rates to 3, 5, or 10 million units tion of patients who do not respond to 12 weeks of treat-(MU) of interferon alfa-2b, given thrice weekly, and to ment wi