𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A pilot randomized controlled trial of sleep therapy in Parkinson's disease: effect on patients and caregivers

✍ Scribed by Iracema Leroi; Peter Baker; Pam Kehoe; Emily Daniel; E Jane Byrne


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
128 KB
Volume
25
Category
Article
ISSN
0885-6230

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

Objective

By means of a controlled trial, to investigate the efficacy, tolerability and feasibility of a multi‐component sleep therapy intervention versus basic sleep hygiene education in PD patients with sleep disturbances and their live‐in carers.

Methods

Patient‐carer dyads were randomised to either of the two interventions. Quantitative measures of sleep, psychiatric and overall functioning were administered at baseline and two weeks after the intervention to patients and carers.

Results

Sleep disturbances in the PD patients improved significantly in both the groups. Between group comparisons in both carers and patients revealed no significant differences on any outcome measures. The intervention was found to be well tolerated, feasible and could easily be translated into the clinical setting.

Conclusions

This pilot study makes the case for further, more rigorous study of pragmatic, non‐pharmacological interventions for sleep disturbances in PD. Copyright © 2010 John Wiley & Sons, Ltd.


📜 SIMILAR VOLUMES


A randomized, double-blind, placebo-cont
✍ Fabrizio Stocchi; Rupam Borgohain; Marco Onofrj; Anthony H.V. Schapira; Mohit Bh 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 446 KB 👁 1 views

## Abstract Safinamide is an α‐aminoamide with both dopaminergic and nondopaminergic mechanisms of action evaluated as an add‐on to dopamine agonist (DA) therapy in early‐stage PD. In this 24‐week, double‐blind study, patients with early PD receiving a stable dose of a single DA were randomized to

Controlled pilot study of the effects of
✍ Lauren H. Craig; Anna Svircev; Michael Haber; Jorge L. Juncos 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 1 views

## Abstract The objectives of this study is to examine the effects of neuromuscular therapy (NMT) on motor and nonmotor symptoms in Parkinson's disease (PD). Thirty‐six subjects with PD were randomly assigned to NMT or music relaxation (MR, or active control). Subjects received treatment twice a we

Increasing access to specialty care: A p
✍ E. Ray Dorsey; Lisa M. Deuel; Tiffini S. Voss; Kara Finnigan; Benjamin P. George 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB 👁 1 views

## Abstract We conducted a randomized, controlled pilot trial to evaluate the feasibility of providing subspecialty care via telemedicine for patients with Parkinson's disease residing in a remote community located ∼130 miles from an academic movement disorders clinic. Study participants were rando

Double-blind, randomized, controlled tri
✍ Matthew B. Stern; Kenneth L. Marek; Joseph Friedman; Robert A. Hauser; Peter A. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB 👁 1 views

## Abstract Rasagiline (__N__‐propargyl‐1(__R__)‐aminoindan) mesylate is a potent, selective, and irreversible monoamine oxidase‐B inhibitor. This study was designed to evaluate the safety, tolerability, and preliminary efficacy of rasagiline monotherapy in early Parkinson's disease (PD) patients n

Effect of sleep deprivation on motor per
✍ Birgit Högl; Cecilia Peralta; Thomas C. Wetter; Oscar Gershanik; Claudia Trenkwa 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 39 KB 👁 1 views

## Abstract Animal research provides evidence that sleep deprivation influences the dopamine system. Knowledge about the effect of sleep deprivation on motor performance in patients with Parkinsons disease is scarce. This study examines the influence of total and partial sleep deprivation compared

Employment, medical absenteeism, and dis
✍ Alexei Korchounov; Gregory Bogomazov 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB

## Abstract The objective of this study was to test the impact of entacapone (ENT) addition to levodopa with a decarboxylase inhibitor (LD) in full‐time–employed patients with Parkinson's disease (PD), focusing on retirement rates, medical absenteeism, self‐perception of disability, as well as moto