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A Pilot Evaluation of the Safety, Tolerability, Pharmacokinetics, and Effectiveness of Memantine in Pediatric Patients with Attention-Deficit/Hyperactivity Disorder Combined Type

✍ Scribed by Findling, Robert L.; McNamara, Nora K.; Stansbrey, Robert J.; Maxhimer, Rebecca; Periclou, Antonia; Mann, Allison; Graham, Stephen M.


Book ID
120365152
Publisher
Mary Ann Liebert
Year
2007
Tongue
English
Weight
208 KB
Volume
17
Category
Article
ISSN
1044-5463

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## Abstract Tolcapone is a potent, reversible catechol‐O‐methyltransferase (COMT) inhibitor with both peripheral and central activity. It has been demonstrated to improve motor function and allow levodopa dose reductions in Parkinson's disease (PD) patients who are experiencing either a stable resp