A physiologically-based pharmacokinetic model for 2,3,7,8-tetrachlorodibenzo-p-dioxin
β Scribed by Hon-Wing Leung; Dennis.J. Paustenbach; Melvin E. Andersen
- Book ID
- 119022722
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 177 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0045-6535
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Concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rat liver and adipose tissue, and hepatic ethoxyresorufin O-deethylase (EROD) activity were studied subsequent to a single subcutaneous injection of TCDD. Two types of experiments were performed to study: (a) time-dependent changes foll
## Abstract The contaminant 2,3,7,8βtetrachlorodibenzoβ__p__βdioxin (TCDD) is a prototype compound of a whole class of halogenated aromatic hydrocarbons termed βdioxinlikeβ contaminants present in food, human tissue, mothers milk, and environmental samples. Among the various adverse effects caused