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A Photoaffinity Analogue of Discodermolide Specifically Labels a Peptide in β-Tubulin †

✍ Scribed by Xia, Shujun; Kenesky, Craig S.; Rucker, Paul V.; Smith, Amos B.; Orr, George A.; Horwitz, Susan Band

Book ID
127045147
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
970 KB
Volume
45
Category
Article
ISSN
0006-2960

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Synthesis of Photoaffinity-Labeling Analogue of Alternariolide (AM-Toxin I), a Host-Specific Phytotoxin. -In order to get more information about the structure of the binding site of alternariolide the title analogue (XI) is synthesized. It is noteworthy that (XI) shows a biological activity as stro