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A Phase I/II Clinical Trial to Evaluate a Combination of Recombinant Human Platelet-Derived Growth Factor-BB and Recombinant Human Insulin-Like Growth Factor-I in Patients with Periodontal Disease

✍ Scribed by Howell, T. Howard; Fiorellini, Joseph P.; Paquette, David W.; Offenbacher, Steven; Giannobile, William V.; Lynch, Samuel E.


Book ID
121193249
Publisher
American Academy of Periodontology
Year
1997
Tongue
English
Weight
625 KB
Volume
68
Category
Article
ISSN
0022-3492

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## Abstract ## Objective To evaluate CAT‐192, a recombinant human antibody that neutralizes transforming growth factor Ξ²1 (TGFΞ²1), in the treatment of early‐stage diffuse cutaneous systemic sclerosis (dcSSc). ## Methods Patients with SSc duration of <18 months were randomly assigned to the place