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A Phase I/II Clinical Trial in Localized Prostate Cancer of an Adenovirus Expressing Nitroreductase with CB1984

✍ Scribed by Patel, Prashant; Young, J Graham; Mautner, Vivien; Ashdown, Daniel; Bonney, Sarah; Pineda, Robert G; Collins, Stuart I; Searle, Peter F; Hull, Diana; Peers, Elizabeth; Chester, John; Wallace, D Michael; Doherty, Alan; Leung, Hing; Young, Lawrence S; James, Nicholas D


Book ID
121448531
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
316 KB
Volume
17
Category
Article
ISSN
1525-0016

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## Background: A phase i trial involving patients with advanced prostate cancer was conducted to assess the safe administration of dendritic cells (dc) and hla-a0201-specific prostate-specific membrane antigen (psma) peptides (psm-p1 or -p2). thirty-three of the phase i participants were subsequent